Coronary Microvascular Dysfunction: Epidemiology, Clinical Presentation, Diagnosis and Treatment

In a significant number of patients with symptoms angina pectoris or myocardial infarction ischemic changes in the myocardium, according to results instrumental research methods, there is no hemodynamically stenosis coronary arteries. these cases, vasospastic microvascular dysfunction considered cause heart disease. Coronary caused by several pathological mechanisms that structural and functional disorders bed heart. Clinical groups include ischemia without obstructive artery disease (primary dysfunction), combination atherosclerosis, damage iatrogenic nature. Diagnostics carried out on basis non-invasive invasive which make it possible clarify nature choose an effective nondrug drug treatment. The prognosis for poor, due development cardiovascular complications death, high risk disability, decrease quality life patients.